Anti-APP Delta C31 (C-terminal)
SKU: BTL-AGR-A-02341 | Host: Rabbit | Brand: Agrisera
₹ 0.00
| Cat Number | AS21 4571 |
|---|---|
| Category | Primary Antibody |
| Pack Size | 100 µl |
| Description | The Alzheimer amyloid precursor protein (APP) is a transmembrane protein whose abnormal processing is associated with the pathogenesis of Alzheimer’s disease. APP695 lacking the protease inhibitor domain is the predominant form in neuronal tissues. APP695 is cleaved by caspases into the 664-residue amino (N)-terminal fragment that lacks the carboxyl C-terminal 31-residues (APP delataC31) and the 31-residues C-terminal fragment (APP-C31). APP delta C31 potentially plays pathophysiological roles in neuronal death. |
| Applications | ELISA (ELISA), Immunolocalisation (IL), Western blot (WB) |
| Immunogen | KLH-conjugated synthetic peptide corresponding to the C-terminal of the caspase 3-cleaved human APP (aa 658-664 of human APP695) UniProt: P05067 |
| Host | Rabbit |
| Form | Liquid |
| Molecular Weight | 86.9 | 96 kDa |
| Dilution Range | 1:500 - 1: 1000 (Immunocytochemistry), 1:1000 - 1: 3000 (WB) |
| Uniprot Number | P05067 |
| Purity | Serum. Contains 0.05% sodium azide. |
| Specie Reactivity | Human, mouse, rat |
| Expected Reactivity | Species of your interest not listed? Contact us |
| Storage | Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
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| Note | The product is for research use only |