Anti-GLO1 | Glyoxalase I (clone 6F10)
SKU: BTL-AGR-A-02338 | Host: Rat | Brand: Agrisera
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| Cat Number | AS21 4568 |
|---|---|
| Category | Primary Antibody |
| Pack Size | 100 µg |
| Description | Glyoxalase I (GLO1) is an enzyme that plays a role in the detoxification of methylglyoxal (MG), a side-product of glycolysis, via condensation with glutathione to produce S-lactoyl-glutathione. GLO1 is a zinc metalloenzyme whose crystal structure has been solved. The bacterial and yeast enzymes are monomeric while the mammalian one is homodimeric and its sequence is well conserved. GLO1 is found over-expressed in some tumors. GLO1 has also been suggested to be involved in anxiety diseases, autism, and Alzheimer’s disease. |
| Applications | ELISA (ELISA), Immunofluorescence (IF), Western blot (WB) |
| Immunogen | Recombinant, full-length mouse GLO1 UniProt: Q9CPU0 fused to GST |
| Clonality | Monoclonal |
| Host | Rat |
| Form | Liquid |
| Molecular Weight | 27 kDa (mouse, 29 kDa (human, simian) |
| Dilution Range | 1 : 1000 (WB) |
| Uniprot Number | Q9CPU0 |
| Purity | Proprietary affinity chromatography in PBS. Contains 50% glycerol, filter sterilized. |
| Specie Reactivity | Human, simian, mouse |
| Expected Reactivity | Species of your interest not listed? Contact us |
| Storage | Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
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| Note | The product is for research use only |