Anti-5MeC | 5-Methylcytosine (clone 5MC-CD) biotinylated
SKU: BTL-AGR-A-02335 | Host: Mouse | Brand: Agrisera
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| Cat Number | AS21 4560 |
|---|---|
| Category | Primary Antibody |
| Pack Size | 50 µg at 1 µg/µl |
| Description | DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. Therefore it is part of the epigenetic code and is also the most well characterized epigenetic mechanism. DNA methylation results in addition of a methyl group to DNA — for example, to the number 5 carbon of the cytosine pyrimidine ring — which involves reduction in gene expression. In adult somatic tissues, DNA methylation typically occurs in a CpG dinucleotide context; non-CpG methylation is prevalent in embryonic stem cells. |
| Applications | Western blot (WB) |
| Immunogen | BSA-conjugated 5-Methylcytosine |
| Clonality | Monoclonal |
| Host | Mouse |
| Form | Liquid |
| Dilution Range | 1 : 1000 (WB) |
| Purity | Purified IgM in PBS. Contains 50 % glycerol, filter sterilized, biotinylated. |
| Specie Reactivity | Chlamydmonas me-1 cells, mouse embryonic stem cells |
| Expected Reactivity | DNA with 5-Methylcytosine (methylated DNA) |
| Storage | Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
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| Note | The product is for research use only |