Anti-Histone H2B (Schizosaccharomyces pombe)
SKU: BTL-AGR-A-02333 | Host: Rabbit | Brand: Agrisera
₹ 0.00
| Cat Number | AS21 4558 |
|---|---|
| Category | Primary Antibody |
| Pack Size | 50 µl |
| Description | In the eukaryotic cells, DNA is packaged repetitively into nucleosomes by means of interactions among two molecules of four classes of histone, H2A, H2B, H3 and H4. Each of the histone proteins has an evolutionarily conserved amino-terminal ‘tail’ that protrudes from the nucleosome. This tail is the target of numerous diverse signaling pathways, resulting in the addition of many post-translational modifications. These modifications include phosphorylation, acetylation, methylation, ADP-ribosylation and mono-ubiquitination. Many important new modifications within the structured core and the carboxy-terminal tail regions of histones are also being identified. It is becoming increasingly clear that these modifications represent crucial regulatory events that govern the accessibility and function of the genome. |
| Applications | Chromatin immunoprecipitation (ChIP), Western blot (WB) |
| Immunogen | Synthetic peptide corresponding to N-terminal Schizosaccharomyces pombe histone H2B, SAAEKKPASKAPAGKA, UniProt: P04913 |
| Clonality | Polyclonal |
| Host | Rabbit |
| Form | Liquid |
| Molecular Weight | 13.8 | 17, 24-25 kDa (unmodified and mono-ubiquinated H2B) |
| Dilution Range | 1 : 1000 (WB) |
| Uniprot Number | P04913 |
| Purity | Serum. Contains 0.05% sodium azide. |
| Specie Reactivity | Schizosaccharomyces pombe |
| Expected Reactivity | Species of your interest not listed? Contact us |
| Storage | Store at -20°C; make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
| View Document | |
| Product Url | View Document |
| Note | The product is for research use only |