Anti-ASY1 | Asynaptic phenotype protein 1 (monoclonal)
SKU: BTL-AGR-A-00238 | Host: Mouse | Brand: Agrisera
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| Cat Number | AS08 338 |
|---|---|
| Category | Primary Antibody |
| Pack Size | 50 µg |
| Description | Pairing and synapsis of homologous chromosomes is required for normal chromosome segregation and the exchange of genetic material via recombination during meiosis. Synapsis is complete at pachytene following the formation of a tri-partite proteinaceous structure known as the synaptonemal complex (SC). In yeast, HOP1 is essential for formation of the SC, and localises along chromosome axes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica (BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutants that display decreased fertility due to severely reduced synapsis of homologous chromosomes. Analysis of these genes has indicated that they play a similar role to HOP1 in pairing and formation of the SC through localisation to axial/lateral elements of the SC. |
| Applications | ELISA (ELISA), Western blot (WB) |
| Immunogen | KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 UniProt: A7TVU8 |
| Clonality | Monoclonal |
| Host | Mouse |
| Form | Lyophilized |
| Molecular Weight | 66.3 kDa |
| Dilution Range | 1: 10 000 (ELISA), 1: 1000 (WB) |
| Uniprot Number | A7TVU8 |
| Purity | Total IgG. Protein G purified purified from Cell culture supernatant. |
| Specie Reactivity | Triticum aestivum |
| Expected Reactivity | Triticum aestivum |
| Reconstitution | For reconstitution add 50 µl of sterile water/tube |
| Storage | Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube. |
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| Note | The product is for research use only |